General Cell Based Assays
Abcam Autophagy Assay Kit
Autophagy Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Sigma Aldrich Fine Chemicals Biosciences Direct DetectR Assay free
Quantity OptionsDDAC00010-GR 50 CardsDDAC00010-4P 200 CardsDDAC00010-8P 400 CardsThe Direct Detect Assay-free Cards are desgined for use in the the Direct Detect Spectrometer. The card contains four hydrophilic polytetrafluoroethylene (PTfE) membrane positions sized for easy sample application and surrounded by a hydrophobic ring to retain analyzed sample within the IR beam. A 2 muL sample volume is recommended in order to assure proper sample application drying and measurement.The Assay-free card can be inserted into the system and analyzed immediately after preparation. The Direct Detect spectrometer has a built in drying system that will automatically dry the sample to the point where it will give an accurate reading. The Direct Detect Assay-free card is intended for a one-time protein application however already prepared cards can be stored and reread later.
BPS Bioscience Inc CD38 INHIBITOR SCREENING ASSAY
CD38 Inhibitor Screening Assay Kit (Hydrolase Activity)The CD38 Inhibitor Screening Assay Kit (Hydrolase Activity) is designed to measure the glycohydrolase activity of CD38 for screening and profiling applications. The CD38 assay kit comes in a convenient 96-well format, with purified recombinant CD38 enzyme, its substrate N6-etheno-NAD (-NAD), and CD38 assay buffer for 100 enzyme reactions. In addition, the kit includes the CD38 inhibitor apigenin for use as a control inhibitor.
Eurofins Discoverx cAMP Hunter eXpress GCGR CHO-K1 GPCR Assay, 2-Plate Kit. (95-0042E2CP2M)
The cAMP Hunter GCGR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. glucagon) based activation of GCGR GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type GCGR, a naturally Gs coupled GPCR. Upon activation of GCGR, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx HitHunter cGMP Assay, 2,400 dp (384-well). (90-0039M)
The HitHunter cGMP Assay is a detection kit offering a robust, sensitive and easy-to-use assay to measure intracellular cGMP levels. This product uses EFC technology, and contains ED-tagged cGMP, anti-cGMP antibody, and pure EA. Upon application to a cell which contains endogenous, untagged cGMP, the anti-cGMP antibody will be sequestered by binding to this untagged cGMP, allowing for EFC between the tagged cGMP and soluble EA. This will produce a proportional level of chemiluminescent signal. This kit may be used with Eurofins DiscoverX cell lines as well as cell lines from other sources. This detection kit contains reagents for 6 plates (384 well). For detailed product information, visit www.discoverx.com/products-applications/biochemical-assays.
Abcam DCF ROS/RNS Assay Kit (biofluids, culture supernatant, cell lysates)
DCF ROS/RNS Assay Kit (biofluids, culture supernatant, cell lysates)
The product is subject to the following: Abcam Restricted Use Statement
BPS Bioscience Inc EIF2AK2 Kinase Assay Kit, 96-well plate, 100 reactions, ADP-Glo™ detection, PKR enzyme supplied, kinase substrate, ATP, assay buffer, stability 6 months
EIF2AK2 Kinase Assay Kit, 96-well plate, 100 reactions, ADP-Glo™ detection, PKR enzyme supplied, kinase substrate, ATP, assay buffer, stability 6 months
Abcam INOSINE QUANTIFICATION ASSAY K ..
INOSINE QUANTIFICATION ASSAY K ..
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx KILR Detection Kit, 200 dp (96-well). (97-0001S)
The KILR Detection Kit is a detection kit intended for use with KILR cell lines or pools when running ADCC or other lysis-based assays. This kit contains exogenous EA as well as EFC substrate to allow for detection of lysis-based release of ProLabel-tagged KILR reporter protein. This kit contains all components required to assay 2 plates (96-well). For detailed product information, User manual and COA, visit www.discoverx.com/products/reagents/detection-kit-97-0001s.
Eurofins Discoverx PathHunter Tocilizumab Bioassay Kit, 10-Plate. (93-1045B3-00110)
The PathHunter Tocilizumab Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. IL-6) induced dimerization of IL-6ST and IL-6R. receptors. This product uses EFC technology. The cell line included overexpresses IL-6ST target protein fused to PK alongside IL-6R target protein fused to EA. Upon ligand-induced dimerization of IL-6ST and IL-6R, detectable EFC signal is produced. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Eurofins Discoverx PathHunter eXpress IL18R1/IL18RAP Dimerization Assay, 2pl Kit. (93-1044E3CP5M)
The PathHunter IL18R1/IL18RAP Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. IL-18) induced dimerization of IL18R1/IL18RAP receptors. This product uses EFC technology. The cell line included overexpresses IL18R1 target protein fused to PK alongside IL18RAP target protein fused to EA. Upon ligand-induced dimerization of IL18R1/IL18RAP, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.