General Cell Based Assays
Abcam LDL Uptake Assay Kit Cell-Based
LDL Uptake Assay Kit Cell-Based
The product is subject to the following: Abcam Restricted Use Statement
Revvity Health Sciences Inc HTRF mAb Anti-6His XL665-Conjugate, 5,000 Assay Points
HTRF mAb Anti-6His XL665-Conjugate, 5,000 Assay Points
Eurofins Discoverx cAMP Hunter eXpress CXCR3 CHO-K1 GPCR Assay, 10-Plate Kit. (95-0054E2CP2L)
The cAMP Hunter CXCR3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CXCL11/I-TAC) based activation of CXCR3 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type CXCR3, a naturally Gi/Go coupled GPCR. Upon activation of CXCR3, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF HMGB1 Detection Kit, 500 Assay Points
HTRF HMGB1 Detection Kit, 500 Assay Points
Eurofins Discoverx PathHunter Human 4-1BB (CD137) Signaling Cell-Based Assay Kit (U2OS)
The PathHunter Human 4-1BB (CD137) (NIK) Signaling Stable Cell Line Assay (U2OS) measures CD137 signal by activation-induced stabilization of NIK. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Cayman Chemical cGAS Stop Solution, 1 mL
cGAS Stop Solution has been tested and formulated to work exclusively with Cayman’s cGAS Inhibitor Screening Assay Kit (Item No. 701930).
Abcam Mevastatin, HMG-CoA reductase inhibitor, 50MG
MW 390.5 Da, Purity >98%. Potent HMG-CoA reductase inhibitor. Proapoptotic, able to arrest cells in G₁ by down-regulation of CDK4, CDK6 and cyclin D1 and up-regulation of p21 and p27.
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress cyno CXCR1 HEK 293 β-Arrestin GPCR Assay, 2pl Kit. (93-0980E1CCP0M)
The PathHunter cyno CXCR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CXCL8/IL8) based activation of cyno CXCR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged cyno CXCR1 and EA-tagged β-Arrestin-2. Activation of cyno CXCR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Cynomolgus monkey version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Pertuzumab Bioassay Kit, 2-Plate. (93-1042Y3-00095)
The PathHunter Pertuzumab Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses heregulin-β2-induced dimerization of ErbB2 and EGFR receptors. This product uses EFC technology. The cell line included overexpresses ErbB2 target protein fused to PK alongside ErbB3 target protein fused to EA. Upon ligand-induced dimerization of ErbB2 and ErbB3, detectable EFC signal is produced. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Eurofins Discoverx AssayComplete Cell Culture Kit-110, (92-3110G)
AssayComplete Cell Culture Kit-110 is an optimized media kit intended for use in culturing and propagating Eurofins DiscoverX cell lines. This kit contains the base medium, relevant serum, and pen/strep required to produce a full cell culture medium for optimal cell culture results. This product is provided as a 3-component kit which will produce approximately 550 mL of finished media. Please refer to cell line specific datasheet to determine the recommended cell culture kit. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Eurofins Discoverx PathHunter eXpress GPR97 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0410E2ACP1L)
The PathHunter GPR97 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR97 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR97 and EA-tagged β-Arrestin-2. Activation of GPR97 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter™ Human CRHR1 Gs Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human CRHR1 Gs Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CRHR1 (GPCR) activity via increased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human OXER1 Total GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human OXER1 Stable Cell Line Total GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure OXER1 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human LPA1 (EDG2) Activated GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human LPA1 (EDG2) Stable Cell Line Activated GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure EDG2 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human PTGER4 β-Arrestin Cell-Based Assay Kit (BHK-21)
The PathHunter Human PTGER4 β-Arrestin Stable Cell Line Assay (BHK-21) contains a stable clonal cell line used to measure rPTGER4 (GPCR) activity via recruitment of β-Arrestin2. Rat protein. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.